Please use this identifier to cite or link to this item: https://repositorio.ufpa.br/jspui/handle/2011/8397
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dc.creatorSÁ, Andrea Lima de-
dc.creatorBAHIA, Carlomagno Pacheco-
dc.creatorDIAS, Ivanira Amaral-
dc.creatorBATISTA, C.-
dc.creatorLEAL, Walace Gomes-
dc.creatorPINHO, André Luís Santos de-
dc.creatorHOUZEL, Jean Christophe-
dc.creatorDINIZ, Cristovam Wanderley Picanço-
dc.creatorPEREIRA JÚNIOR, Antônio-
dc.creatorCORREA, Vânia Castro-
dc.date.accessioned2017-05-16T12:25:37Z-
dc.date.available2017-05-16T12:25:37Z-
dc.date.issued2016-05-
dc.identifier.citationSÁ, Andrea Lima de de et al. Morphometric analysis of feedforward pathways from the primary somatosensory area (S1) of rats. Braziian Journal Medical and Biological Research, Ribeirão Preto, v. 49, n. 6, e5115, 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600601&lng=pt&nrm=iso>. Acesso em: 16 maio 2017. Epub 10-Maio-2016. <http://dx.doi.org/10.1590/1414-431X20155115>.pt_BR
dc.identifier.issn1414-431Xpt_BR
dc.identifier.urihttp://repositorio.ufpa.br/jspui/handle/2011/8397-
dc.description.abstractWe used biotinylated dextran amine (BDA) to anterogradely label individual axons projecting from primary somatosensory cortex (S1) to four different cortical areas in rats. A major goal was to determine whether axon terminals in these target areas shared morphometric similarities based on the shape of individual terminal arbors and the density of two bouton types: en passant (Bp) and terminaux (Bt). Evidence from tridimensional reconstructions of isolated axon terminal fragments (n=111) did support a degree of morphological heterogeneity establishing two broad groups of axon terminals. Morphological parameters associated with the complexity of terminal arbors and the proportion of beaded Bp vs stalked Bt were found to differ significantly in these two groups following a discriminant function statistical analysis across axon fragments. Interestingly, both groups occurred in all four target areas, possibly consistent with a commonality of presynaptic processing of tactile information. These findings lay the ground for additional work aiming to investigate synaptic function at the single bouton level and see how this might be associated with emerging properties in postsynaptic targets.pt_BR
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dc.description.provenanceApproved for entry into archive by Luciana Alcantara (lalcantara@ufpa.br) on 2017-05-16T12:25:37Z (GMT) No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Artigo_MorphometricAnalysisFeedforward.pdf: 3228566 bytes, checksum: 656d5f3cbb8b3f4dbd387c8626ebefba (MD5)en
dc.description.provenanceMade available in DSpace on 2017-05-16T12:25:37Z (GMT). No. of bitstreams: 2 license_rdf: 0 bytes, checksum: d41d8cd98f00b204e9800998ecf8427e (MD5) Artigo_MorphometricAnalysisFeedforward.pdf: 3228566 bytes, checksum: 656d5f3cbb8b3f4dbd387c8626ebefba (MD5) Previous issue date: 2016-05en
dc.languageporpt_BR
dc.publisherUniversidade Federal do Parápt_BR
dc.relation.ispartofBrazilian Journal of Medical and Biological Researchpt_BR
dc.rightsAcesso Abertopt_BR
dc.subjectMorfometriapt_BR
dc.subjectMorfologiapt_BR
dc.subjectAnálise estatísticapt_BR
dc.subjectNeurociênciaspt_BR
dc.titleMorphometric analysis of feedforward pathways from the primary somatosensory area (S1) of ratspt_BR
dc.typeArtigo de Periódicopt_BR
dc.publisher.countryBrasilpt_BR
dc.publisher.initialsUFPApt_BR
dc.citation.volume49pt_BR
dc.citation.issue6pt_BR
dc.citation.spage1pt_BR
dcterms.citation.epage10pt_BR
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