Por favor, use este identificador para citar o enlazar este ítem: https://repositorio.ufpa.br/jspui/handle/2011/8397
Tipo: Artigo de Periódico
Fecha de publicación : may-2016
Autor(es): SÁ, Andrea Lima de
BAHIA, Carlomagno Pacheco
DIAS, Ivanira Amaral
LEAL, Walace Gomes
PINHO, André Luís Santos de
HOUZEL, Jean Christophe
DINIZ, Cristovam Wanderley Picanço
CORREA, Vânia Castro
Título : Morphometric analysis of feedforward pathways from the primary somatosensory area (S1) of rats
Citación : SÁ, Andrea Lima de de et al. Morphometric analysis of feedforward pathways from the primary somatosensory area (S1) of rats. Braziian Journal Medical and Biological Research, Ribeirão Preto, v. 49, n. 6, e5115, 2016. Disponível em: <http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2016000600601&lng=pt&nrm=iso>. Acesso em: 16 maio 2017. Epub 10-Maio-2016. <http://dx.doi.org/10.1590/1414-431X20155115>.
Resumen : We used biotinylated dextran amine (BDA) to anterogradely label individual axons projecting from primary somatosensory cortex (S1) to four different cortical areas in rats. A major goal was to determine whether axon terminals in these target areas shared morphometric similarities based on the shape of individual terminal arbors and the density of two bouton types: en passant (Bp) and terminaux (Bt). Evidence from tridimensional reconstructions of isolated axon terminal fragments (n=111) did support a degree of morphological heterogeneity establishing two broad groups of axon terminals. Morphological parameters associated with the complexity of terminal arbors and the proportion of beaded Bp vs stalked Bt were found to differ significantly in these two groups following a discriminant function statistical analysis across axon fragments. Interestingly, both groups occurred in all four target areas, possibly consistent with a commonality of presynaptic processing of tactile information. These findings lay the ground for additional work aiming to investigate synaptic function at the single bouton level and see how this might be associated with emerging properties in postsynaptic targets.
Palabras clave : Morfometria
Análise estatística
Series/Report no.: Brazilian Journal of Medical and Biological Research
ISSN : 1414-431X
País: Brasil
Editorial : Universidade Federal do Pará
Sigla da Instituição: UFPA
metadata.dc.rights: Acesso Aberto
Aparece en las colecciones: Artigos Científicos - ICS

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