Dissertações em Neurociências e Comportamento (Mestrado) - PPGNC/NTPC

URI Permanente para esta coleçãohttps://repositorio.ufpa.br/handle/2011/10670

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Efeitos da estrutura gramatical e da entonação da voz na identificação de frases do tipo ordem e sugestão.
(Universidade Federal do Pará, 2016-10-06) PANTOJA, Maelly Larissa Mendes; SILVA, Maria Luisa da; http://lattes.cnpq.br/2101884291102108; PARACAMPO, Carla Cristina Paiva; lattes.cnpq.br/9018003546303132
The objective of this study was to evaluate whether Grammatical Structure and Intonation of voice are relevant variables for the identification of a verbal stimulus as an Order and/or a Suggestion, or even, if one or other of these two characteristics is more relevant to the occurrence of this identification. The study included 180 students (between 18 and 30 years) of several undergraduate courses, which were exposed to fourteen different phrases which varied in content, Grammatical Structure and Intonation. The phrases in Portuguese were presented with the Grammatical Structure of Order (three phrases) and Suggestion (three phrases), each presented with two Intonations - Order and Suggestion - phrase in Mandarin was also presented with the same two intonations; totaling 14 phrases. The phrases were presented randomly to participants, through an audio recording. The task was to record on worksheet answer the corresponding option so that identified be the phrase: Order, Suggestion or None of the Above. The participants were divided into two groups, Group I and Group II, which differed only in the voice used in audio recording. The results of the Set 1 - composed by phrases with Structure of Order and Intonation of Suggestion and Order - showed that the participants of Group I chose to 55.2% and the Group II 58.9% of the time the option Order when the Grammatical Structure does not match the Intonation and that 93.3% and 93.7% of responses of participants' choices of Groups I and II, respectively, was the option Order when the Grammatical Structure corresponded to Intonation. The results of the Set 2 - composed by phrases with Structure of Suggestion and Intonation of Suggestion and Order - indicated that the Group I 48.5% of phrases were identified as Order and in Group II 54.4% as Suggestion when the Grammatical Structure does not match the intonation and that in Group I and II 91.1% and 89.3% of the phrases, respectively, were identified as Suggestion when the Grammatical Structure corresponded to Intonation. The results of the Set 3 - composed of phrases in Mandarin with Intonation of Order and Suggestion - showed that the participants of Group I were 85.6% and in Group II 70% of the time the option None of the Above when the Intonation was of Order and that the participants of Group II were 85.6% of Group I and 82.2% the option None of the Above when the Intonation was Suggestion. These results indicate that the control by the Grammatical Structure prevailed under the control by the Intonation of the voice in the identification of phrases as being of type Order or Suggestion.
Acesso aberto (Open Access)
Relação entre neurogênese hipocampal e história clínica de pacientes adultos portadores de epilepsia refratária do lobo temporal.
(Universidade Federal do Pará, 2018-09-13) GAMA, Jessica Silva; SOUSA, Regina Célia Gomes de; http://lattes.cnpq.br/5576436464955236; LIMA, Silene Maria Araújo de; http://lattes.cnpq.br/8961057812067156
Epilepsy is a neurological disorder characterized by the permanent predisposition of the brain to generate epileptic seizures, which affects about 1% of the world population. In Brazil, the disease can reach 2% to 4% of the population. Most patients have a good prognosis for drug treatment, however 30% of patients are refractory to treatment. Among the epilepsies that do not present a good prognosis is the Temporal Lobe Epilepsy (ELT). ELT is characterized morphologically by a selective loss of hippocampal neurons, concomitantly with increased hippocampal neurogenesis. It is believed that this exacerbated neurogenesis contributes to epileptogenesis (onset of epilepsy); however, the role of this increased neurogenesis in patients with TLE remains unknown. We used hippocampus from patients with epilepsy, who underwent a surgical procedure in which unilateral hippocampal resection was performed. From the analysis of the same, a possible relationship between neurogenic patterns and the evolution of the disease was investigated. Interviews with patients who underwent surgery demonstrated that the triggering event (precipitant) of epilepsy occurred in the first years of life of the patients. In addition, they were high intensity events, and also presented a high frequency of epileptic seizures and drug refractoriness. Immunohistochemical analysis of hippocampi showed equivalently that there was a perceptible dispersion of the granule cell layer, indicating a possible ectopic migration in labeling for neuroblasts (immature neurons), which are generated in neurogenesis. The results obtained in this work are pioneer, given that they are based on both clinical and histopathological findings, and the relationship between hippocampal neurogenesis and clinical history proposes a new research vision. These findings may also help in a new perspective of differential treatment in temporal lobe epilepsies.

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